发明名称 |
PROCESS FOR VIRUS DEACTIVATION IN THE PRESENCE OF POLYALKYLENE GLYCOL AND THE PHARMACEUTICAL PREPARATION THUS OBTAINED |
摘要 |
PCT No. PCT/IB95/00019 Sec. 371 Date Jun. 28, 1996 Sec. 102(e) Date Jun. 28, 1996 PCT Filed Jan. 10, 1995 PCT Pub. No. WO95/09657 PCT Pub. Date Apr. 13, 1995The invention relates to a pharmaceutical preparation comprising a plasma protein wherein said preparation is free of infectious agents as well as essentially free of denaturation products and is obtainable by a method that encompasses the following steps: a) addition of a polyether and a chaotropic agent to a solution comprising the plasma protein, optional lyophilization of the solution; b) inactivation of infectious agents in the presence of the polyether by a physio-chemical or chemical treatment, and c) removal of the polyether and the chaotropic agent.
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申请公布号 |
HU9600906(D0) |
申请公布日期 |
1996.05.28 |
申请号 |
HU19960000906 |
申请日期 |
1994.10.06 |
申请人 |
IMMUNO AKTIENGESELLSCHAFT |
发明人 |
BARRETT,NOEL;DORNER,FRIEDRICH;EIBL,JOHANN |
分类号 |
A61K38/16;A61K35/16;A61K39/395;A61L2/00;C07K16/06 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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