| 发明名称 |
PROCESS FOR PRODUCING RING-SUBSTITUTED 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENES AND 3-AMINO-CHROMANES |
| 摘要 |
<p>Isoxazole derivs. of formula (I) and their acid-addn. salts and solvates are new: In (I) R = 1-4C alkyl, allyl or cyclopropylmethyl; R1 = H, 1-4C alkyl, allyl, cyclopropylmethyl or aryl(1-4C)alkyl; X = CH2 or O; y = 4-R2-5-R3-3-isoxazolyl or 3-R2-4-R3-5-isoxazolyl; R2 and R3 = H, 1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio, OH, NH2, CN or Ph. Pref. x = CH2; R and R1 = 1-4C alkyl, esp. n-Pr; R2 and R3 = H.</p> |
| 申请公布号 |
HUT72659(A) |
申请公布日期 |
1996.05.28 |
| 申请号 |
HU19950000495 |
申请日期 |
1992.02.07 |
| 申请人 |
ELI LILLY AND CO. |
发明人 |
HOECHSTETTER,CRAIG STEVEN;HUSER,DIANE LYNN;SCHAUS,JOHNE MEHNERT;TITUS,ROBERT DANIEL |
| 分类号 |
A61K31/42;A61K31/353;A61K31/4015;A61P1/00;A61P1/14;A61P9/12;A61P13/02;A61P15/00;A61P25/00;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/26;A61P25/32;A61P43/00;C07C225/18;C07C225/20;C07C255/42;C07C323/29;C07D261/08;C07D261/10;C07D261/12;C07D261/14;C07D261/18;C07D311/04;C07D311/20;C07D311/58;C07D413/04;C07D413/10;(IPC1-7):C07D311/58 |
主分类号 |
A61K31/42 |
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