摘要 |
The invention pertains to a process for the production of a pharmaceutical composition effective for controlling in a recipient host mammal, particularly man, immune reactions of the type that are involved in graft of foreign tissue or cells, particularly bone marrow cells of allogeneic or even xenogeneic origin, or in immunodeficiency-linked diseases, which pharmaceutical composition is characterized by an active principle consisting of pooled transferrin obtained from a number of donors sufficient to allow the pool to contain all the phenotypic information required to ensure for an induction of tolerance against antigens in an immunodepressed host grafted with said antigens, after that host had been administered an amount of such pooled transferrins effective to induce said tolerance. |