发明名称 COMPOSITION CONTAINING POOLED TRANSFERRINS AS AN ACTIVE PRINCIPLE FOR THE INDUCTION OF IMMUNE TOLERANCE AGAINST ANTIGENS
摘要 The invention pertains to a process for the production of a pharmaceutical composition effective for controlling in a recipient host mammal, particularly man, immune reactions of the type that are involved in graft of foreign tissue or cells, particularly bone marrow cells of allogeneic or even xenogeneic origin, or in immunodeficiency-linked diseases, which pharmaceutical composition is characterized by an active principle consisting of pooled transferrin obtained from a number of donors sufficient to allow the pool to contain all the phenotypic information required to ensure for an induction of tolerance against antigens in an immunodepressed host grafted with said antigens, after that host had been administered an amount of such pooled transferrins effective to induce said tolerance.
申请公布号 WO9614862(A1) 申请公布日期 1996.05.23
申请号 WO1995EP04317 申请日期 1995.11.03
申请人 CELLENA AG;I.S.I. S.P.A.;PIERPAOLI, WALTER 发明人 PIERPAOLI, WALTER
分类号 A61K38/40 主分类号 A61K38/40
代理机构 代理人
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