发明名称 LIPID CLEAVAGE ENZYME
摘要 A membranous enzyme not yet described in the state-of-the-art can be extracted from cellular membrane fractions of blood leukocytes or monocytes/macrophages. Also disclosed is the use of substrates of this enzyme to prepare medicaments that contain these substrates as pharmaceutical active substance. These medicaments are useful to direct pharmacologically active substances to target cells and to enrich target cells with said substances. Also disclosed are invitro research systems containing this enzyme used to detect other substrates of this enzyme.
申请公布号 CA2204908(A1) 申请公布日期 1996.05.23
申请号 CA19952204908 申请日期 1995.11.09
申请人 BOEHRINGER MANNHEIM GMBH 发明人 ZILCH, HARALD;OPITZ, HANS-GEORG;HERRMANN, DIETER
分类号 A61K31/675;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7076;A61K38/54;A61K45/00;A61K47/48;A61K49/00;A61P31/12;A61P35/00;A61P37/00;A61P39/02;A61P43/00;C07H19/10;C07H19/16;C07H19/20;C12N5/06;C12N9/16;C12Q1/42;C12Q1/44;(IPC1-7):C12N9/16;C07H19/23 主分类号 A61K31/675
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