Cyclosporin containing multiple emulsions

摘要

The invention relates to an oral multiple emulsion pre concentrate comprising a surface active agent, ethanol a lipophilic and/or an amphiphilic solvent. The composition comprising from about 5 to about 30 % by weight of cyclosporin, from about 5 to about 30 % by weigh of tocopheryl polyethylene glycol carboxylic acid ester, from about 5 to about 20 % by weight of ethanol, from about 20 to about 55 % by weight of a lipophylic solvent and/or from about 10 to about 55 % by weight of an amphiphilic solvent, and if desired from about 10 to about 20 % by weight of co-tenside.