发明名称 STABILIZATION OF FAT EMULSION
摘要 PURPOSE: To stabilize a fat emulsion without developing its appearance change and fat particle growth, by mixing an oil-in-water type fat emulsion with another injection agent such as glucose or electrolyte in the presence of a nonionic surfactant. CONSTITUTION: The stability of a fat emulsion is markedly improved by mixing an oil-in-water type fat emulsion with an injection agent in the presence of a nonionic surfactant. The injection is e.g. glucose, an electrolyte, a nutrient replenisher such as an amino acid, microelement(s), vitamine(s), antibiotic or carcinostatic. The fat emulsion can be prepared, for example, by emulsifying a kind of oil-and-fat selected from vegetable oils such as soybean oil, coconut oil, sesame oil and perilla oil, animal oils such as whale oil and fish oil, and medium chain fatty acid triglycerides with at least one kind of emulsifier selected from purified soybean phospholipids and hydrogenated soybean phospholipids, etc. The nonionic surfactant is pref. polyoxyethylene hardened castor oil-50, polyoxyethylene hardened castor oil-60, or polysorbate-80.
申请公布号 JPH08127529(A) 申请公布日期 1996.05.21
申请号 JP19940289010 申请日期 1994.10.27
申请人 MORISHITA ROUSSEL KK 发明人 ARII KANJI;YAMASHITA SHUNZO;KUNIBA YUKIFUMI
分类号 A61K9/107;A61K31/23;A61K47/44;A61P3/00;A61P3/12;(IPC1-7):A61K9/107 主分类号 A61K9/107
代理机构 代理人
主权项
地址