The present invention provides a method of producing a transgenic non-human animal, which method comprises incorporating into the genome of the non-human animal at least one nucleotide sequence (A) comprising a sequence (i) encoding a nitroreductase which is capable of converting a prodrug into a cytotoxic drug.
申请公布号
WO9614420(A1)
申请公布日期
1996.05.17
申请号
WO1995GB02596
申请日期
1995.11.06
申请人
CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED;AGRICULTURAL AND FOOD RESEARCH COUNCIL;CLARK, JOHN;CONNORS, THOMAS;GUSTERSON, BARRY;KNOX, RICHARD
发明人
CLARK, JOHN;CONNORS, THOMAS;GUSTERSON, BARRY;KNOX, RICHARD
