IN VITRO TISSUE AND ORGAN EQUIVALENT MODELS

摘要

This invention is directed to an organ equivalent of the cornea part of the eye made using tissue culturing systems. The method of constructing the cornea equivalent results in a structure analogous to the eye cornea in vivo. The cornea equivalent is an in vitro model on the eye, which can be used for transplantation or implantation in vivo or for screening compounds in vitro. This invention is also directed to the use of endothelial cells in other tissue and organ equivalents to promote basement membrane development.