Synthese fluorierter Ether

摘要

Fluorinated ethers of the formula: wherein R is hydrogen, fluorine, alkyl of 1 to 6 carbon atoms, or fluoroalkyl of 1 to 6 carbon atoms, R min is hydrogen, alkyl of 1 to 6 carbon atoms, or fluoroalkyl of 1 to 6 carbon atoms, and R sec is fluorine, alkyl of 1 to 6 carbon atoms or fluoroalkyl of 1 to 6 carbon atoms, e.g. Desflurane, are prepared by fluorinating a corresponding ether of formula: with a solid transition metal fluoride fluorinating agent such as cobaltic fluoride.