| 摘要 |
<p>The present invention relates to influenza virus strains which may reliably be propagated to high titer in hosts such as embryonated eggs. High yield strains, including reassortment influenza viruses and influenza viruses exhibiting chimeric viral surface molecules, such as chimeric HA and/or NA surface molecules, are described. Further, methods for the production of such high yield influenza A, B, and/or C virus strains are described. These high yield viruses may be used in the production of anti-viral vaccines and the manufacture of chimeric influenza viruses.</p> |
