发明名称 |
Method of preparing monopotassium L-malate and its monohydrate |
摘要 |
An aqueous solution of L-malic acid and potassium ion is prepared having a pH of no more than 6.8. The aqueous solution is cooled to initiate crystallization of a potassium salt of L-malic acid, and the aqueous mixture obtained is allowed to stand at a pH of 5.3 to 6.8 until it substantially reaches liquid-solid equilibrium. The resultant crystals of monopotassium L-malate monohydrate are collected therefrom. The monopotassium L-malate monohydrate thus obtained may be dried to give the corresponding anhydrate. Monopotassium L-malate and its monohydrate are stable, non-hygroscopic crystals.
|
申请公布号 |
US4124636(A) |
申请公布日期 |
1978.11.07 |
申请号 |
US19780876698 |
申请日期 |
1978.02.10 |
申请人 |
TANABE SEIYAKU CO., LTD. |
发明人 |
CHIBATA, ICHIRO;SUMI, AKIHIKO;OHTSUKI, OSAMU |
分类号 |
C07C59/245;C07C51/00;C07C51/41;C07C67/00;(IPC1-7):C07C59/22 |
主分类号 |
C07C59/245 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|