Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same

摘要

A biodegradable porous drug delivery device for controllably releasing a pharmacological agent is disclosed which comprises a hollow tube closed at both ends having an interior surface and an exterior surface, the tube formed of a mixture of polycaprolactone and a pore-creating agent, the tube further comprising channels formed between the interior surface and the exterior surface and a pharmacological agent filled into the hollow tube for controllable release through the channels of the tube. Methods of manufacturing the biodegradable porous drug delivery device are also disclosed.