METHOD OF AVERMECTIN PREPARING

摘要

FIELD: biotechnology, antibiotics for agriculture. SUBSTANCE: parental extract from mycelium of culture-producer is extracted repeatedly with organic solvent that does not mix with water. If necessary, the secondary extract is purified by chromatography methods as in the known ones but the repeated extraction is carried out at alkaline condition. Method is used for avermectin preparing by microbiology procedure. EFFECT: increased specific activity of product, diminished content of ballast matters.