| 摘要 |
The present invention relates to supramolecules which are formed by at least two components. Each component comprises an effector molecule and at least one nucleic acid chain. The nucleic acid chains of each component are complementary to nucleic acid chains on other components and thus are able to bind the components of the supramolecule by the formation of double stranded nucleic acid chains between the complementary chains. The present invention also relates to a method of making the supramolecules of the present invention. The nucleic acid chains are preferably DNA, RNA and may also contain structural analogues of DNA or RNA. Effector molecules that may be used to form the supramolecules include, but are not limited to polypeptides, lipids, sugars. These effector molecules may impart chemical, physical properties to the supramolecule that include, but are not limited to hydrophobicity, hydrophilicity, electron conductivity, fluorescence, radioactivity, biological activity, cellular toxicity, catalytic activity, molecular and cellular recognition and in vivo transport selectivity.
|
