| 摘要 |
<p>A method of treating human patients is provided by the intrapulmonary delivery of a pharmaceutically active peptide formulation (5). The formulation is automatically released in an aerosolized form from a hand-held, self-contained, portable device (40) comprised of a means (23) for automatically releasing a measured amount of drug into the inspiratory flow path (29) of a patient in response to information obtained from a means (37) for measuring the inspiratory flow rate and determining the inspiratory volume of a patient. Reproducible dosing is obtained by providing for automatic release at the same inspiratory flow rate and inspiratory volume each time drug is released. The device includes a timer to enable a patient to take a drug at the same time each day. Further, overadministration of hormone formulation is avoided by providing a pre-programmed microprocessor (26) designed to avoid overdosing.</p> |
