| 发明名称 |
STRETCH-ACTIVATED CATION CHANNEL AND ANTISENSE OLIGONUCLEOTIDES THERETO |
| 摘要 |
An antisense oligonucleotide of 10 to 35 nucleotides in length that can hybridize with a region of the .alpha.1 subunit of the SA-Cat channel gene DNA or mRNA is provided, together with pharmaceutical compositions containing and methods utilizing such antisense oligonucleotide.
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| 申请公布号 |
CA2202881(A1) |
申请公布日期 |
1996.05.09 |
| 申请号 |
CA19952202881 |
申请日期 |
1995.10.25 |
| 申请人 |
JEWISH HOSPITAL OF ST. LOUIS;TRUSTEES OF DARTMOUTH COLLEGE |
发明人 |
HRUSKA, KEITH A.;BARRY, ELIZABETH L. R.;DUNCAN, RANDALL L.;FRIEDMAN, PETER A. |
| 分类号 |
C12N15/09;A61K31/70;A61K38/00;A61K48/00;A61P9/12;A61P43/00;C07H21/04;C07K14/705;C12N15/113;(IPC1-7):C07H21/00 |
主分类号 |
C12N15/09 |
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