摘要 |
Compounds, 1,3-dihydro-1-{1-[piperidin-4-yl]piperidin-4-yl}-2H-benzimidazol-2-ones and 1,3-dihydro-1-{4-amino-1-cyclohexyl}-2H-benzimidazol-2-ones and derivatives thereof, their preparation, method of use and pharmaceutical compositions are described. These compounds are endowed with antimuscarinic activity and are useful in the treatment and/or prevention of myopia (commonly known as nearsightedness).
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申请人 |
MERCK & CO., INC.;THOMPSON, WAYNE, J.;SUGRUE, MICHAEL, F.;RANSOM, RICHARD, W.;MALLORGA, PIERRE, J.;BELL, IAN, M.;SMITH, ANTHONY, M. |
发明人 |
THOMPSON, WAYNE, J.;SUGRUE, MICHAEL, F.;RANSOM, RICHARD, W.;MALLORGA, PIERRE, J.;BELL, IAN, M.;SMITH, ANTHONY, M. |