发明名称 |
CREATING AN AEROSOLIZED FORMULATION OF INSULIN |
摘要 |
Devices, packaging and methodology for efficiently and repeatably creating aerosolized bursts of an insulin containing formulation are disclosed. Devices are hand-held, self-contained units which are automatically actuated at the same release point in a patient's inspiratory flow cycle. The release point is automatically determined either mechanically or, more preferably calculated by a microprocessor which receives data from a sensor making it possible to determine inspiratory flow rate and inspiratory volume. Actuation of the device forces insulin formulation through a porous membrane (3) of the container (1) which membrane has pores having a diameter in the range of about 0.25 to 3.0 microns, preferably 0.25 to 1.5 microns. |
申请公布号 |
CA2203129(A1) |
申请公布日期 |
1996.05.09 |
申请号 |
CA19952203129 |
申请日期 |
1995.10.27 |
申请人 |
ARADIGM CORPORATION |
发明人 |
LLOYD, PETER M.;SCHUSTER, JEFFREY A.;RUBSAMEN, REID M.;LLOYD, LESTER J. |
分类号 |
A61J7/02;A61J7/04;A61K9/00;A61K9/12;A61K38/02;A61K38/28;A61K39/12;A61M11/00;A61M15/00;A61M16/00;A61M16/14;C07K5/00;C07K7/00;C07K17/00 |
主分类号 |
A61J7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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