Phosphonosulfonate squalene synthetase inhibitor salts and method
摘要
New salt forms of the phosphonosulfonate squalene synthetase inhibitor <CHEM> are provided which include the calcium, the t-butylamine salt, t-octylamine salt and the dehydroabietylamine salt. These salts inhibit cholesterol biosynthesis and therefore are used in lowering serum cholesterol and in treating atherosclerosis.
申请公布号
EP0710665(A1)
申请公布日期
1996.05.08
申请号
EP19950307618
申请日期
1995.10.26
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
PENDRI, YADAGIRI;CHEN, CHUNG-PIN;KUCERA, DAVID J.;MARTINEZ, EDUARDO J.;PANSEGRAU, PAUL D.;THOTTATHIL, JOHN K.;TIMMINS, PETER