发明名称 |
Method and cyclic carbonates for nucleotide analogues |
摘要 |
An improved method for the preparation of acyclic nucleotide analogues comprises first condensing a cyclic carbonate with a purine or pyrimidine base and then reacting the alkylated base with an activated phosphonate. Novel cyclic carbonates are employed to yield the desired phosphonylmethoxyalkyl nucleotide analogues.
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申请公布号 |
US5514798(A) |
申请公布日期 |
1996.05.07 |
申请号 |
US19950388125 |
申请日期 |
1995.02.13 |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
BISCHOFBERGER, NORBERT W.;KENT, KENNETH M. |
分类号 |
C07D473/34;C07F9/6561;(IPC1-7):C07D473/34;C07D473/16;C07D317/36;C07B43/04 |
主分类号 |
C07D473/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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