| 发明名称 |
Cell culture of hepatitis A virus |
| 摘要 |
Hepatitis A virus is attenuated in virulence by in vitro passage in susceptible cell cultures, without prior passage in a subhuman primate. This process results in a live, attenuated hepatitis A virus vaccine suitable for human disease prevention.
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| 申请公布号 |
US5514376(A) |
申请公布日期 |
1996.05.07 |
| 申请号 |
US19930016486 |
申请日期 |
1993.02.10 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
GIESA, PAULA A.;PROVOST, PHILIP J.;HILLEMAN, MAURICE R. |
| 分类号 |
A61K39/29;C12N7/08;(IPC1-7):A61K39/12;C12N7/00 |
主分类号 |
A61K39/29 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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