发明名称 Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
摘要 Substituted imidazolyl-alkyl-piperazine and diazepine derivatives of Formula A: <IMAGE> wherein R1, R2, R3, R4, R5, m, n and q are defined as in the specification, and the pharmaceutically acceptable salts thereof. The compounds have calcium entry blocking activity with selectivity for cerebral blood vessels, and have protective activity against some of the deleterious effects resultant upon cerebral ischemia.
申请公布号 US5514800(A) 申请公布日期 1996.05.07
申请号 US19930124518 申请日期 1993.09.20
申请人 SYNTEX PHARMACEUTICALS, LTD. 发明人 PASCAL, JEAN C.;LEE, CHI-HO;ALPS, BRIAN J.;PINHAS, HENRI;WHITING, ROGER L.;MACFARLANE, CALUM B.;BERANGER, SERGE
分类号 C07D233/54;C07D403/06;(IPC1-7):C07D403/06;C07D243/08 主分类号 C07D233/54
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