| 摘要 |
<p>The invention describes a process for the preparation of a tablet containing an oxytocin receptor antagonist as active ingredient. The tablet is prepared by forming a powder blend of the active ingredient of 1-(7,7-Dimethyl)-2-endo-(2S-amino-4-(methylsulfonyl)-butyramido)bicyclo(2.2.1)heptan-1-yl)methanesulfonyl)-4-(2-methylphenyl)piperazine, or a pharmaceutically acceptable salt thereof, with a first binder and a diluent; wet granulating the powder blend with a solution of a second binder in water to form granules; drying the granules to remove water; and compressing the dried granules into a desired tablet form.</p> |
