METHOD FOR PEPTIDE SYNTHESIS BASED ON N-(N'-NITROSOCARBAMOYL)AMINO ACIDS

摘要

Novel method for peptide synthesis using an N-[N'-nitroso-(R')carbamoyl]amino acid as the starting compound. The compound is separated into N2, R'OH and N-carboxyanhydride of formula (II). The compound (II) together with an amino acid or peptide with at least one free alpha -amino function is introduced into a reactive medium to obtain a dipeptide or a higher peptide than the added peptide.