发明名称 Asymmetric transformation of pipecolic acid, a precursor of levobupivacaine and analogues thereof
摘要 A process for the preparation of optically-enriched pipecolic acid as a salt with an optically-active acid, comprises asymmetric transformation of pipecolic acid, as a racemic mixture or a mixture enriched in the opposite enantiomer from that desired, with the optically-active acid in a solvent comprising an acid that causes racemisation, in the absence of aldehyde.
申请公布号 AU3614195(A) 申请公布日期 1996.05.02
申请号 AU19950036141 申请日期 1995.10.09
申请人 CHIROSCIENCE LIMITED 发明人 CHRISTOPHER JAMES LOCK
分类号 C07D211/60 主分类号 C07D211/60
代理机构 代理人
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