摘要 |
N1-Cyclohexyl-N3-phenyl-urea or thiourea derivs. of formula (I) and their acid addn. salts are new: X = O or S; R1 = t-Bu or Ph (opt. mono- or disubstd. by 1-3C alkyl, OH or 1-3C alkoxy (opt. substd. in 2- or 3-position by di- 1-3C alkylamino, pyrrolidino, piperidino or hexamethyleneimino)); R2 = H, Me or Et; R3 = 1-3C alkyl; R4 = 1-12C alkyl, 3-12C mono- or polyunsatd. alkenyl or alkynyl opt. monosubstd. by Ph (substd. by R5 and R6), 7-12C cycloalkyl or Ph substd. by R5 and R6; R5, R6 = H, F, Cl, Br, CF3, 1-4C alkyl or alkoxy; or Ph+R5+R6 = naphthyl.
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申请人 |
DR. KARL THOMAE GMBH, 88400 BIBERACH, DE |
发明人 |
HURNAUS, RUDOLF, DIPL.-CHEM. DR., 88400 BIBERACH, DE;MAIER, ROLAND, DIPL.-CHEM. DR., 88400 BIBERACH, DE;MUELLER, PETER, DIPL.-CHEM. DR., 88441 MITTELBIBERACH, DE;WOITUN, EBERHARD, DIPL.-CHEM. DR., 88400 BIBERACH, DE;MARK, MICHAEL, DR., 88400 BIBERACH, DE;EISELE, BERNHARD, DIPL.-CHEM. DR., 88400 BIBERACH, DE;BUDZINSKI, RALPH-MICHAEL, DIPL.-BIOL. DR., 88400 BIBERACH, DE;HALLERMAYER, GERHARD, DIPL.-CHEM. DR., 88437 MASELHEIM, DE |