发明名称 |
USE OF [R-(Z)]-ALPHA-(METHOXYIMINO)-ALPHA-(1-AZABICYCLO [2.2.2] OCT-3-YL) ACETONITRILE TO REDUCE AMYLOID BETA A4 FORMATION IN ALZHEIMER'S DISEASE |
摘要 |
A method of enhancing amyloid precursor protein processing along a nonamyloidogenic pathway in patients suffering from, or at risk of developing, Alzheimer's disease and a method of treatment or prophylaxis of Alzheimer's disease by reducing .beta.A4 production in patients suffering from, or at risk of developing, Alzheimer's disease comprising administering to the patient an effective, non-toxic amount of an acetonitrile compound, use of the compound in preparation of a medicament for use in the method and a composition for use in the method.
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申请公布号 |
CA2203670(A1) |
申请公布日期 |
1996.05.02 |
申请号 |
CA19952203670 |
申请日期 |
1995.10.17 |
申请人 |
SMITHKLINE BEECHAM P.L.C. |
发明人 |
GRAY, CAROL WENDY;MARKWELL, ROGER EDWARD;HAWKINS, JULIE |
分类号 |
A61K31/435;(IPC1-7):A61K31/435 |
主分类号 |
A61K31/435 |
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地址 |
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