CIRCULARLY PERMUTED LIGANDS AND CIRCULARLY PERMUTED CHIMERIC MOLECULES
摘要
The present invention provides for circularly permuted ligands which possess specificity and binding affinity comparable to or greater than the specificity and binding affinity of the original (unpermuted) ligand. The invention further provides for novel fusion proteins comprising a circularly permuted ligand fused to one or more proteins of interest.
申请公布号
WO9527732(A3)
申请公布日期
1996.05.02
申请号
WO1995US04468
申请日期
1995.04.06
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, RE;PASTAN, IRA;KREITMAN, ROBERT, J.