摘要 |
<p>Method (400) for enriching nucleated fetal erythrocytes from maternal whole blood sample is disclosed. Maternal whole blood sample (101) is passed through a gravity-biased, counterflow stabilized charge-flow separator (60) in which nucleated fetal erythrocytes are separated from maternal whole blood sample (101). Separated nucleated fetal erythrocytes are passed through leukocyte-depleting adsorption-filtration matrix (110, 112) to obtain leukocyte depleted nucleated fetal erythrocytes (440).</p> |