发明名称 |
p53as Protein and antibody therefor |
摘要 |
The invention comprises antibodies both polyclonal and monoclonal, to p53as and to at least a portion of human p53 intron 10 sequence encoding SLRPFKALVREKGHRPSSHSC which is related to p53as sequences. All of the above find utility in studying p53 and p53as and their relative expressions which is believed important for detection and control of malignant cells and their susceptibility to treatment agents. The antibodies can detect the presence of p53as and related sequences and when injected into cells could cause cell cycle arrest. |
申请公布号 |
EP0709397(A1) |
申请公布日期 |
1996.05.01 |
申请号 |
EP19950610034 |
申请日期 |
1995.06.14 |
申请人 |
HEALTH RESEARCH, INC. |
发明人 |
KULESZ-MARTIN, MOLLY F. |
分类号 |
G01N33/53;A61K38/00;A61K39/395;A61P35/00;C07K14/47;C07K14/525;C07K16/00;C07K16/24;C07K16/30;C07K16/32;C12N5/10;C12N15/02;C12N15/09;C12P21/02;C12P21/08;C12R1/91;G01N33/574;G01N33/577 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|