CONJUGATES OF A POLYPEPTIDE OR OLIGOPEPTIDE WITH A LOW MOLECULAR WEIGHT LIPOPHILIC COMPOUND

摘要

Disclosed are conjugates of a polypeptide or oligopeptide with a low molecular weight lipophilic compound, the peptide and lipophilic group being covalently linked to one another either directly or via a connecting element, with the exception of (a) conjugates in which the peptide component consists of hirudin or peptide structurally derived from hirudin or a peptide derivative with hirudin-like properties, and (b) conjugates whose peptide component has been hydrophobically modified during their biosynthesis.