5,6-dihydro-4h-imidazo[2',1':2,3]imidazo-[4,5,1-ij]quinoline and 4,5-dihydroimidazo-[1,2-a]pyrolo[1,2,3-cd]benzimidazole derivatives, their preparation and application in therapeutics

摘要

The invention discloses compounds formula (I) <IMAGE> (I) in which n represents the number 1 or 2, X represents a hydrogen atom or indicates that the phenyl ring to which it is attached is substituted by one or two substituents independently chosen from halogen, C1-C3 alkyl, C1-C3 alkoxy and hydroxyl, and R represents a hydrogen atom, a group of formula -CH2-CO2-R1 (in which R1 represents a hydrogen atom or a C1-C6 alkyl group) or a group of formula -CH2-CO-NR2R3 (in which each of R2 and R3 is independently a hydrogen atom or a C1-C3 alkyl group), or a pharmaceutically acceptable salt thereof, processes for their preparation and their use in the treatment of disorders of GABAergic transmission.