发明名称 |
Method of treating retained pulmonary secretions |
摘要 |
A method of facilitating the clearance of retained pulmonary secretions in a subject using lantibiotics is disclosed. The method comprises administering to the lungs of the subject an effective amount of a lantibiotic. The lantibiotic is preferably administered by topically applying it to the respiratory epithelia, such as by generating an aerosol thereof which is then inhaled by the subject. A preferred lantibiotic for carrying out the present invention is duramycin. The method may be used in treating disorders such as cystic fibrosis, chronic bronchitis, and asthma. Also disclosed is a method of combatting tuberculosis comprising administering a lantibiotic to a subject in need of such treatment.
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申请公布号 |
US5512269(A) |
申请公布日期 |
1996.04.30 |
申请号 |
US19930074315 |
申请日期 |
1993.06.09 |
申请人 |
BURROUGHS WELLCOME, CO.;UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
MOLINA Y VEDIA, LUIS M.;STUTTS, MONROE J.;BOUCHER, JR., RICHARD C.;HENKE, DAVID C. |
分类号 |
A61K9/12;A61K31/4409;A61K31/496;A61K31/7036;A61K38/00;A61K38/04;A61K38/12;A61K38/16;A61K45/00;A61P11/00;A61P11/08;A61P11/12;A61P31/04;A61P31/06;(IPC1-7):A61K9/12 |
主分类号 |
A61K9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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