发明名称 Method of treating cancer tumors with imine porphyrin compounds
摘要 Purified imines of porphyrins, chlorins, bateriochlorins, chlorophylls, bacteriochlorophylls, purpurins, reduced purpurins, verdins, Diels Alder adducts, benzochlorins and metal complexes of the foregoing imines are disclosed. The formulas of the benzochlorinimines and of the benzochlorinimine metal complexes are set forth below: <IMAGE> <IMAGE> In specific examples, M in the metal complexes is a copper cation that is complexed with two of the nitrogens of the benzochlorinimine R' and R'''' are methyl, and R1 through R8 are ethyl.
申请公布号 US5512559(A) 申请公布日期 1996.04.30
申请号 US19950375629 申请日期 1995.01.19
申请人 THE UNIVERSITY OF TOLEDO AND MEDICAL COLLEGE OF OHIO 发明人 SKALKOS, DIMITRIS;SELMAN, STEVEN H.;HAMPTON, JAMES A.
分类号 A61K31/40;A61K31/555;A61P35/00;C07D487/22;(IPC1-7):A61K31/40 主分类号 A61K31/40
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