发明名称 |
POLYMERIC SURFACTANT-ENCAPSULATED MICROBUBBLES AND THEIR USE IN ULTRASOUND IMAGING |
摘要 |
PCT No. PCT/GB94/01923 Sec. 371 Date Mar. 14, 1997 Sec. 102(e) Date Mar. 14, 1997 PCT Filed Sep. 5, 1994 PCT Pub. No. WO95/06518 PCT Pub. Date Mar. 9, 1995The present invention relates to polymer-based gas-containing contrast agents in which microbubbles of gas are encapsulated by non-polymerizable wall-forming block or graft copolymer surfactants. The polymer surfactants are preferably biodegradable and include block and graft copolymers containing linkages of formula (I):-(O)m-CO-O-C(R1R2)-O-CO-(O)n-(I)where R1 and R2 each represent a hydrogen atom or a carbon-attached monovalent organic group, or R1 and R2 together form a carbon-attached divalent organic group and m and n are each zero or 1. |
申请公布号 |
HU9600515(D0) |
申请公布日期 |
1996.04.29 |
申请号 |
HU19960000515 |
申请日期 |
1994.09.05 |
申请人 |
NYCOMED IMAGING A/S |
发明人 |
DUGSTAD,HARALD;FOSS,PER ANTONIUS;KLAVENESS,JO;REDFORD,KEITH;RONGVED,PAL;SKURTVEIT,ROALD;STRANDE,PER |
分类号 |
A61K49/00;A61K49/04;A61K49/22;B01F17/00;B01J13/04;C08G63/08 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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