| 发明名称 |
AQUEOUS SOLUTION INCLUSION COMPLEXES OF BENZOTHIOPHENE COMPOUNDS WITH WATER SOLUBLE CYCLODEXTRINS, AND PHARMACEUTICAL FORMULATIONS THEREOF AND METHODS FOR THEIR PREPARATION |
| 摘要 |
The present invention provides aqueous inclusion complexes of certain known benzothiophene compounds, particularly Raloxifene, and water soluble cyclodextrins. Also provided are pharmaceutical compositions of such inclusion complexes, and methods of using these complexes for inhibiting bone loss and reducing serum cholesterol in mammals.
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| 申请公布号 |
HUT72298(A) |
申请公布日期 |
1996.04.29 |
| 申请号 |
HU19940003567 |
申请日期 |
1994.12.12 |
| 申请人 |
ELI LILLY AND CO. |
发明人 |
BRYANT,HENRY UHLMAN;CULLINAN,GEORGE JOSEPH;FRANCIS,PAUL CLIFTON;MAGEE,DAVID EDWARD;SWEETANA,STEPHANIE ANN;THAKKAR,ARVIND LAVJI |
| 分类号 |
C07D333/56;A61K9/08;A61K31/365;A61K31/38;A61K31/381;A61K31/40;A61K31/4025;A61K31/445;A61K31/4535;A61K31/55;A61K47/40;A61K47/48;A61P3/06;A61P7/00;A61P19/08;A61P19/10;A61P43/00;C08B37/16;(IPC1-7):A61K47/40 |
主分类号 |
C07D333/56 |
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