COMPOUNDS CONTAINING FUSED BICYCLIC NUCLEUS, INTERMEDIATE COMPOUNDS, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION

摘要

FIELD: organic chemistry. SUBSTANCE: product: compounds of the formulawhere X - O or S-(O); n = 1 or 2; m = 0 or 1; Y - CH, O or S-(O)at condition that Y is O or S-(O)only if it is 1; and A -or. These compounds are inhibitors of NEP and ACE of the double action. Compounds where A -orare selective inhibitors of ACE. Also, methods of synthesis of the end and intermediate compounds were given. EFFECT: improved methods of synthesis.