| 摘要 |
PURPOSE: To obtain skin external agent containing a water-soluble rutin and an anti-inflammatory agent as active components, having high stability and excellent anti-inflammatory and beautifying effect, and accordingly capable of exhibiting strong suppressing effect against the inflammation of skin by sunburn and the pigmentation after sunburn. CONSTITUTION: This external agent contains a water-soluble rutin [preferably, α-glycosylrutin of the formula (R is glucose, mannose, etc.); the content of rutin is 10-85wt.%] and an anti-inflammatory agent (preferably, glycyrrhizinic acid, glycyrrhetinic acid, an extract of chamomile, etc.) as active components. The content of the water-soluble rutin is preferably 0.00001-5wt.% in terms of rutin. That of the anti-inflammatory agent is preferably 0.01-3wt.%. Further, α- glycosylrutin of the formula is obtained e.g. by mixing rutin with starchiness such as dextrin followed by an enzymatic reaction. |
