发明名称 |
2, 4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceuticals |
摘要 |
2,4-disulfonyl alpha -phenyl-tert-butyl nitrone and its pharmaceutically acceptable salts are disclosed. These materials are useful as pharmaceutical agents for oral or parenteral, e.g. intravenous administration to patients suffering from acute central nervous system oxidation as occurs in a stroke or from gradual central nervous system oxidation which can exhibit itself as progressive central nervous system function loss. The materials are also used to ameliorate the side effects of oxidative-damage causing antineoplastic disease treatments.
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申请公布号 |
US5508305(A) |
申请公布日期 |
1996.04.16 |
申请号 |
US19950468564 |
申请日期 |
1995.06.06 |
申请人 |
OKLAHOMA MEDICAL RESEARCH FOUNDATION;UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION |
发明人 |
CARNEY, JOHN M. |
分类号 |
A61K31/15;A61K31/185;A61P9/00;A61P25/00;A61P25/28;A61P35/00;A61P39/06;A61P43/00;C07C309/46;(IPC1-7):A61K31/255 |
主分类号 |
A61K31/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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