| 摘要 |
<p>This invention is an apparatus and method for diagnosing cancer in vivo. A laser (12) and tunable dye system (14) generate an output beam which is transported by an optical fiber bundle (18) to a tissue to be examined. Laser induced fluorescence emitted by the tissue is delivered through the bundle (18) to a sensor, which may include a spectrograph (24) and a multi-channel detector (26) for producing a spectrum. The spectrum is analyzed by a computer (28) that diagnoses cancerous tissue using differential normalized fluorescence, wherein the intensity at each wavelength is divided by the integrated area under the spectrum and compared with a normalized spectrum from a normal tissue sample.</p> |
