CERAMIDE 3 DERIVATIVES BASED ON MONOUNSATURATED FATTY ACIDS
摘要
The present invention discloses ceramide 3 derivatives based on monounsaturated fatty acids. A preferred compound is N-oleoylphytosphingosine (Ceramide IIIB). A method for preparing these compounds is also disclosed. The solubility of these compounds is higher than the solubility of the corresponding saturated ceramide 3 derivatives, whereas their stability is comparable to saturated ceramide 3 stabilities. In addition, a method is described for maintaining the water permeability characteristics of the skin by topical application of a formulation containing a monounsaturated ceramide 3 derivative.
申请公布号
WO9610557(A1)
申请公布日期
1996.04.11
申请号
WO1995EP03908
申请日期
1995.10.02
申请人
GIST-BROCADES B.V.;LAMBERS, JOHANNES, WILHELMUS, JACOBUS;VERWEIJ, JAN
发明人
LAMBERS, JOHANNES, WILHELMUS, JACOBUS;VERWEIJ, JAN