| 发明名称 |
SUBSTITUTED ARYL PIPERAZINES AS NEUROKININ ANTAGONISTS |
| 摘要 |
Disclosed are substituted aryl piperazines of Formula (I) which are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis. In particular compounds of Formula (I) are shown to be neurokinin antagonists.
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| 申请公布号 |
CA2199621(A1) |
申请公布日期 |
1996.04.11 |
| 申请号 |
CA19952199621 |
申请日期 |
1995.09.26 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
CHIANG, YUAN-CHING P.;FINKE, PAUL E.;MACCOSS, MALCOLM;MEURER, LAURA C.;MILLER, DANIEL J.;MILLS, SANDER G.;ROBICHAUD, ALBERT J.;SHAH, SHRENIK K. |
| 分类号 |
C07D249/08;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4418;A61K31/4425;A61K31/495;A61K31/505;A61K31/52;A61P11/00;A61P11/08;A61P21/00;A61P25/00;A61P25/02;A61P25/04;A61P25/26;A61P25/28;A61P25/30;A61P37/00;A61P37/06;A61P43/00;C07D213/64;C07D213/65;C07D213/74;C07D233/61;C07D239/42;C07D241/20;C07D257/04;C07D295/12;C07D295/125;C07D471/04;C07D473/18;C07D473/34;C07D487/04;C07D491/04;C07D491/048;C07D495/04;C07D521/00;(IPC1-7):C07D295/15;C07D473/00;C07D475/00;C07D239/48;A61K31/53;C07D213/63 |
主分类号 |
C07D249/08 |
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