| 发明名称 |
1-(3'-fluoro-2',3'-dideoxy- beta -D-ribofuranosyl)-5-substituted pyrimidine nucleosides |
| 摘要 |
A 2',3'-deoxy-3'-fluoro-pyrimidine nucleoside having the formula: <IMAGE> wherein R1 is OH or NH2; R2 is CF3, CH2CH2CH3, <IMAGE> CH2OCH3, CH2SCH3, CH=CH2 CH=CH-CH3, C 3BOND CH, C 3BOND C-CH3 or CH2-C 3BOND CH; or a pharmaceutically acceptable salt thereof. These nucleoside analogs exhibit antiviral activity against HIV.
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| 申请公布号 |
US5506215(A) |
申请公布日期 |
1996.04.09 |
| 申请号 |
US19940354769 |
申请日期 |
1994.12.12 |
| 申请人 |
MEDIVIR AB |
发明人 |
JOHANSSON, KARL N. G.;LINDBORG, BJOEG.;NORINDER, ULF;STENING, GORAN B. |
| 分类号 |
C07H19/06;C07H19/16;(IPC1-7):A61K31/70;C07H19/073 |
主分类号 |
C07H19/06 |
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