Detection of mammalian immunodeficiency viruses

摘要

PCT No. PCT/AU92/00280 Sec. 371 Date Feb. 24, 1994 Sec. 102(e) Date Feb. 24, 1994 PCT Filed Jun. 12, 1992 PCT Pub. No. WO92/22573 PCT Pub. Date Dec. 23, 1992The invention provides peptides having immunological properties in common with the backbone of an immunodominant region of the transmembrane envelope protein of mammalian immunodeficiency viruses, which region comprises a disulphide loop and which region is unexpectedly highly conserved in mammalian immunodeficiency viruses derived from different mammalian sources. The invention also provides method and immunoassay test kits for detection of mammalian immunodeficiency viruses using these above peptides. The invention also relates to antibodies directed against the above peptides, and their use in immunoassays and as immunoadsorbents for mammalian immunodeficiency virus.