发明名称 PROCESS FOR THE ENZYMATIC SEPARATION OF ENANTIOMERS OF RAC-2-OXOTRICYCLO[2.2.1.03.5]HEPTANE-7-CARBOXYLIC ACID AND OF RAC-2-OXOTRICYCLO[2.2.1.03.5]HEPTANE-7-CARBOXYLIC ESTERS
摘要 Compounds of the formula I (I) in which R1 has the meanings mentioned, may be obtained in isomerically pure form from enantiomer mixtures or racemic mixtures by reacting the compound of the formula I in the presence of a lipase or esterase from porcine liver, porcine pancreas, bovine pancreas or from microorganisms such as Candida, Pseudomonas, Mucor, Rhizopus and Aspergillus, or proteases from Bacillus in the presence of water and, if desired, a cosolvent and separating from one another the esters and acids present in the solution obtained.
申请公布号 CA2159777(A1) 申请公布日期 1996.04.05
申请号 CA19952159777 申请日期 1995.10.03
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 HOLLA, WOLFGANG;BECK, GERHARD
分类号 C07C69/757;C12P15/00;C12P41/00;C12R1/07;C12R1/38;C12R1/66;C12R1/72;C12R1/785;C12R1/845;(IPC1-7):C12P41/00 主分类号 C07C69/757
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