发明名称 |
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE |
摘要 |
The present invention comprises dipeptide analogs that inhibit the farnesylation of Ras. These farnesyl-protein transferase inhibitors are characterized by the inclusion of a cyclic amine in the backbone of the dipeptide. Further contained in this invention are chemotherapeutic compositions containing these farnesyl transferase inhibitors and methods for their production.
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申请公布号 |
CA2201347(A1) |
申请公布日期 |
1996.04.04 |
申请号 |
CA19952201347 |
申请日期 |
1995.09.25 |
申请人 |
MERCK & CO., INC. |
发明人 |
DESOLMS, S. JANE;GRAHAM, SAMUEL L. |
分类号 |
C07D207/16;C07D211/60;C07D223/06;C07D401/00;C07D403/00;(IPC1-7):C07D207/16 |
主分类号 |
C07D207/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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