摘要 |
PCT No. PCT/US91/07622 Sec. 371 Date Jun. 22, 1992 Sec. 102(e) Date Jun. 22, 1992 PCT Filed Oct. 21, 1991 PCT Pub. No. WO92/06985 PCT Pub. Date Apr. 30, 1992.Novel synthetic oligomers of unique three-dimensional structure comprising homologous and heterologous blocks, some of which may self-associate are described. Also disclosed is a synthetic oligonucleotide that includes 5-fluorocytosine residues at positions corresponding to methylation sites of DNA-cytosine methyltransferase and a method for preparing such a molecule.
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