AQUEOUS NASAL SUSPENSION

摘要

This invention relates to an aqueous nasal suspension comprising a cyclodextrin and hardly soluble drug whose one part by weight requires 1000 or more parts by weight of water to yield a homogeneous mixture at 25.degree.C under one atmospheric pressure and whose stability constant in relation to the cyclodextrin calculated by solubility method is not greater than 1000. The aqueous nasal suspension of this invention enhances the pharmacological efficacy of a hardly soluble drug in water, improves its retention in nasal mucosa, and prolongs the action of the drug so that the frequency of administration can be decreased. Therefore, this nasal suspension can be used as a meritorious topical nasal preparation assuring improved patient compliance.