| 摘要 |
<p>A novel DNA coding for a steroidal formone receptor-like protein has been obtained from a cDNA library of human fetal lungs and its structure has been determined. Further a protein coded for by the gene of the DNA has been isolated, identified and named an ECDN protein. Also another protein coded for by the DNA deficient in part of the genes has been isolated, identified and named an ECDN small-molecule protein. It has been found that the ECDN small-molecule protein is expressed in various cancer cells. Therefore it is expected that the diagnosis and cure of cancer will become possible by the analysis of gene expression of the ECDN protein and the ECDN small-molecule protein in the specimen tissues. Development of new drugs can be expected by finding out natural and synthetic compounds that specifically bind to the above proteins.</p> |
