| 发明名称 |
METHODS FOR THE TREATMENT OF INFLAMMATORY JOINT DISEASE |
| 摘要 |
The use of compounds that block complement component C5 or its active fragments C5a and/or C5b (such compounds collectively referred to as "C5 blockers") to treat established joint inflammation (arthritis) is disclosed. Administration of such C5 blockers has been found to: 1) arrest and/or reduce inflammation in joints which are already inflamed, and 2) inhibit the spread of inflammation to unaffected joints.
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| 申请公布号 |
CA2198706(A1) |
申请公布日期 |
1996.03.28 |
| 申请号 |
CA19952198706 |
申请日期 |
1995.09.21 |
| 申请人 |
ALEXION PHARMACEUTICALS, INC. |
发明人 |
WANG, YI;MATIS, LOUIS |
| 分类号 |
A61K45/00;A61K31/34;A61K31/395;A61K38/00;A61K39/395;A61P29/00;C07D307/94;C07K16/18;C07K16/40;(IPC1-7):A61K39/395;C12Q1/02;G01N33/555;G01N33/564 |
主分类号 |
A61K45/00 |
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